MONDO_0007915 (systemic lupus erythematosus) is an autoimmune multi-organ disease typically associated with vasculopathy and autoantibody production. Most patients have antinuclear antibodies (ANA). The presence of anti-dsDNA or anti-Smith antibodies are highly-specific. Also known as: Lupus, SLE, SLE - lupus erythematosus, systemic, disseminated lupus erythematosus, lupus erythematosus, systemic, systemic lupus erythematosus (disease), systemic lupus erythematosus susceptibility to.