A myelodysplastic syndrome characterized by a deletion between bands q31 and 33 on chromosome 5. The number of blasts in the bone marrow and blood is <5%. The bone marrow is usually hypercellular or normocellular with increased number of often hypolobated megakaryocytes. The peripheral blood shows macrocytic anemia. This syndrome occurs predominantly but not exclusively in middle age to older women. The prognosis is good and transformation to acute leukemia is rare. (WHO, 2001). The disease is myelodysplastic syndrome associated with isolated del(5q) (Monarch Disease Ontology entry MONDO_0007925). Also known as: 5Q minus syndrome, 5Q- syndrome, 5q- syndrome, 5q- syndrome, refractory macrocytic anaemia due to 5q deletion, 5q- syndrome, refractory macrocytic anemia due to 5q deletion, chromosome 5q deletion syndrome, macrocytic anemia, refractory, due to 5q deletion, somatic, myelodysplastic syndrome associated with isolated del (5q) chromosome Abnormality.