An autosomal dominant tumor predisposition disorder caused by pathogenic variants in the SDHD gene, characterized by an increased risk of paraganglioma and pheochromocytoma, as well as an increased risk of renal cell carcinoma and gastrointestinal stromal tumors (GIST). The disease is pheochromocytoma/paraganglioma syndrome 1 (Monarch Disease Ontology identifier MONDO_0008192). Also known as: SDHD paraganglioma, SDHD-related tumor predisposition, paraganglioma caused by mutation in SDHD, paragangliomas 1, paragangliomas 1, with or without deafness, paragangliomas type 1.