Monarch Disease Ontology identifier MONDO_0008283 (Cronkhite-Canada syndrome) (CCS) is a rare gastrointestinal (GI) polyposis syndrome characterized by the association of non-hereditary GI polyposis with the cutaneous triad of alopecia, nail changes and hyperpigmentation. Also known as: gastric Cronkhite Canada polyposis, gastrointestinal polyposis-ectodermal changes syndrome, gastrointestinal polyposis-skin pigmentation-alopecia-fingernail changes syndrome.