proximal renal tubular acidosis (Monarch Disease Ontology entry MONDO_0008369) (pRTA) is a tubular kidney disease characterized by impaired ability of the proximal tubule to reabsorb bicarbonate from the glomerular filtrate leading to hyperchloremic metabolic acidosis. Also known as: Type 2 RTA, Type 2 renal tubular acidosis, pRTA, renal tubular acidosis type 2.