Smith-Magenis syndrome (MONDO_0008434, a Monarch Disease Ontology id) (SMS) is a complex genetic disorder characterized by variable intellectual deficit, sleep disturbance, craniofacial and skeletal anomalies, psychiatric disorders, and speech and motor delay. Also known as: 17p11.2 microdeletion syndrome, SMITH-Magenis syndrome, SMS, Smith Magenis Syndrome, Smith-Magenis syndrome, Isolated cases, chromosome 17P11.2 deletion syndrome, chromosome 17p11.2 deletion syndrome.