congenital adrenal hyperplasia due to 17-alpha-hydroxylase deficiency (MONDO_0008730) is a very rare form of congenital adrenal hyperplasia (CAH) characterized by glucocorticoid deficiency, hypergonadotrophic hypogonadism and severe hypokalemic hypertension. Also known as: 17-alpha-hydroxylase/17,20-lyase deficiency, CAH due to 17-alpha-hydroxylase deficiency, combined 17-hydroxylase/17,20-lyase deficiency.