Monarch Disease Ontology term MONDO_0008800 (microphthalmia with limb anomalies), also known as ophthalmo-acromelic syndrome (OAS), is a rare developmental disorder characterized by bilateral microphthalmia or anophthalmia, synostosis, syndactyly, oligodactyly and/or polydactyly. Also known as: MLA, OAS, Ophthalmoacromelic syndrome, Waardenburg anophthalmia syndrome, anophthalmia-syndactyly syndrome, ophthalmoacromelic syndrome.