A Griscelli syndrome characterized by silvery gray sheen of the hair, hypopigmentation of the skin and neurological impairment without immunodeficiency that has material basis in mutations in the MYO5A gene on chromosome 15q21.2. The disease is Monarch Disease Ontology id MONDO_0008962 (Griscelli syndrome type 1). Also known as: GS1, Griscelli syndrome with neurological impairment, Griscelli syndrome, cutaneous and neurological type, Griscelli-PruniC)ras syndrome type 1, Griscelli-Pruniéras syndrome type 1, hypopigmentation-neurologic impairment syndrome.