Wolcott-Rallison syndrome (WRS) is a very rare genetic disease, characterized by permanent neonatal diabetes mellitus (PNDM) with multiple epiphyseal dysplasia and other clinical manifestations, including recurrent episodes of acute liver failure. The disease is Wolcott-Rallison syndrome (Monarch Disease Ontology id MONDO_0009192). Also known as: WRS, early-onset diabetes mellitus with multiple epiphyseal dysplasia.