Monarch Disease Ontology identifier MONDO_0009249 (hereditary fructose intolerance) (HFI) is an autosomal recessive disorder of fructose metabolism, resulting from a deficiency of hepatic fructose-1-phosphate aldolase activity and leading to gastrointestinal disorders and postprandial hypoglycemia following fructose ingestion. HFI is a benign condition when treated, but it is life-threatening and potentially fatal if left untreated. Also known as: Fructosaemia, Fructose Intolerance, Hereditary, fructose intolerance, fructose intolerance, hereditary, fructose-1,6-bisphosphate aldolase B deficiency, fructosemia, hereditary fructose intolerance syndrome, hereditary fructose-1-phosphate aldolase deficiency.