fructose-1,6-bisphosphatase deficiency (MONDO_0009251) can be described as follows. Fructose-1,6-biphosphatase (FBP) deficiency is a disorder of fructose metabolism characterized by recurrent episodes of fasting hypoglycemia with lactic acidosis, that may be life-threatening in neonates and infants. Also known as: fructose 1 phosphate aldolase deficiency, fructose-1,6-diphosphatase deficiency.