pantothenate kinase-associated neurodegeneration (Monarch Disease Ontology term MONDO_0009319) (PKAN) is the most common type of neurodegeneration with brain iron accumulation (NBIA), a rare neurodegenerative disorder characterized by progressive extrapyramidal dysfunction (dystonia, rigidity, choreoathetosis), iron accumulation on the brain and axonal spheroids in the central nervous system. Also known as: Hallervorden-Spatz disease, Hallervorden-Spatz syndrome, NBIA1, PKAN, neurodegeneration with brain iron accumulation 1, neurodegeneration with brain iron accumulation type 1, pigmentary pallidal degeneration.