Autoimmune polyendocrinopathy type 1, or APECED syndrome, is a genetic disease that manifests in childhood or early adolescence with a combination of chronic mucocutaneous candidiasis, hypoparathyroidism and autoimmune adrenal failure. The disease is Monarch Disease Ontology term MONDO_0009411 (autoimmune polyendocrine syndrome type 1). Also known as: AIRE autoimmune polyendocrinopathy, APECED syndrome, APS type 1, APS1, Autoimmune Polyglandular Syndrome Type 1, MEDAC syndrome, Whitaker syndrom, aire autoimmune polyendocrinopathy.