MONDO_0009693 (plasma cell myeloma) is a bone marrow-based plasma cell neoplasm characterized by a serum monoclonal protein and skeletal destruction with osteolytic lesions, pathological fractures, bone pain, hypercalcemia, and anemia. Clinical variants include non-secretory myeloma, smoldering myeloma, indolent myeloma, and plasma cell leukemia. (WHO, 2001). Also known as: Kahler disease, Kahler's disease, Multiple Myeloma, medullary plasmacytoma, multiple myeloma, multiple myeloma, resistance to, Somatic mutation, multiple myeloma, susceptibility to, Somatic mutation, multiple myeloma/plasma cell myeloma.