Netherton syndrome (Monarch Disease Ontology term MONDO_0009735) (NS) is a skin disorder characterized by congenital ichthyosiform erythroderma (CIE), a distinctive hair shaft defect (trichorrhexis invaginata; TI) and atopic manifestations. Also known as: Comèl-Netherton syndrome, Ichthyosis, Netherton Syndrome, NS, bamboo hair syndrome.