chronic recurrent multifocal osteomyelitis (MONDO_0009813, a Monarch Disease Ontology entry) is chronic non bacterial osteomyelitis (CNO), also known as chronic recurrent multifocal osteomyelitis (CRMO), is a chronic autoinflammatory syndrome that is characterized by multiple foci of painful swelling of bones, mainly in the metaphyses of the long bones, in addition to the pelvis, the shoulder girdle and the spine. Also known as: CNO/CRMO, CRMO, NBO, chronic multifocal osteomyelitis, chronic recurrent multifocal osteomyelitis (disease), non-bacterial osteomyelitis.