MONDO_0009824 (primary hyperoxaluria type 2) can be described as follows. Primary hyperoxaluria (PH) type 2 is a rare disorder of glyoxylate metabolism caused by the deficiency of the enzyme glyoxylate reductase/hydropyruvate reductase (GR/HPR) characterized by a childhood onset with clinical manifestations that include recurrent nephrolithiasis, nephrocalcinosis and end-stage renal disease with subsequent systemic oxalosis. Also known as: D-glycerate dehydrogenase deficiency, GRHPR primary hyperoxaluria, L-glyceric aciduria, primary hyperoxaluria caused by mutation in GRHPR, primary hyperoxaluria type II.