Hyperimmunoglobinemia D with periodic fever (HIDS) is a rare autoinflammatory disease characterized by periodic attacks of fever and a systemic inflammatory reaction (cervical lymphadenopathy, abdominal pain, vomiting, diarrhea, arthralgias and skin signs). The disease is Monarch Disease Ontology id MONDO_0009849 (hyperimmunoglobulinemia D with periodic fever). Also known as: HIDS, hyper-IgD syndrome, hyperimmunoglobinemia D with recurrent fever, hyperimmunoglobulinemia D syndrome, partial mevalonate kinase deficiency.