This syndrome is characterized by intellectual deficit, short stature, obesity, genital abnormalities, and hand and/or toe contractures. It has been described in two brothers and in one isolated case. The patients also present with generalized osteoporosis and a history of frequent fractures. This syndrome is similar to Prader-Willi syndrome, but the hand contractures and osteoporosis, together with the lack of hypotonia, indicate this is a different entity. The disease is urban-Rogers-Meyer syndrome (Monarch Disease Ontology term MONDO_0009905). Also known as: Prader-Willi habitus-osteopenia-camptodactyly syndrome, intellectual disability-short stature-hand contractures-genital anomalies syndrome.