vitamin K-dependent clotting factors, combined deficiency of, type 1 (MONDO_0010187) can be described as follows. Combined vitamin K-dependent clotting factors deficiency (VKCFD) is a congenital bleeding disorder resulting from variably decreased levels of coagulation factors II, VII, IX and X, as well as natural anticoagulants protein C, protein S and protein Z. Also known as: GGCX congenital vitamin K-dependent coagulation factors combined deficiency, congenital vitamin K-dependent coagulation factors combined deficiency caused by mutation in GGCX, hereditary combined deficiency of factors II, VII, IX and X.