syndromic X-linked intellectual disability Lubs type (MONDO_0010283, a Monarch Disease Ontology term) can be described as follows. Distal Xq duplications refer to chromosomal disorders resulting from involvement of the long arm of the X chromosome (Xq). Clinical manifestations vary widely depending on the gender of the patient and on the gene content of the duplicated segment. The prevalence of Xq duplications remains unknown. Also known as: Lubs X-linked intellectual disability syndrome, Lubs X-linked mental retardation syndrome, MECP2 duplication syndrome, MRXSL, X-linked intellectual disability-hypotonia-recurrent infections syndrome, Xq28 (MECP2) duplication, distal duplication Xq, intellectual developmental disorder, X-linked syndromic, Lubs type, X-linked recessive.