Ogden syndrome is a rare, genetic progeroid syndrome characterized by a variable phenotype including postnatal growth delay, severe global developmental delay, hypotonia, non-specific dysmorphic facies with aged appearance and cryptorchidism, as well as cardiac arrthymias and skeletal anomalies. Patients typically present with widely opened fontanels, mainly truncal hypotonia, a waddling gait with hypertonia of the extremities, small hands and feet, broad great toes, scoliosis and redundant skin with lack of subcutaneous fat. The disease is Ogden syndrome (MONDO_0010457). Also known as: N-alpha-acetyltransferase, N-terminal acetyltransferase deficiency, OGDNS, Ogden syndrome, X-linked recessive, X-linked dominant, X-linked malformation and infantile lethality syndrome, premature ageing appearance-developmental delay-cardiac arrhythmia syndrome, premature aging appearance-developmental delay-cardiac arrhythmia syndrome.