Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the NHS gene. The disease is cataract 40 (MONDO_0010544, a Monarch Disease Ontology entry). Also known as: CTRCT40, NHS early-onset non-syndromic cataract, cataract 40 X-linked, cataract 40 with or without microcornea, cataract type 40, early-onset non-syndromic cataract caused by mutation in NHS.