Charcot-Marie-Tooth neuropathy that is inherited in an X-linked manner, and is associated with mutation(s) in the GJB1 gene, encoding gap junction beta-1 protein. The condition is characterized by moderate to severe motor and sensory neuropathy in males, and mild to no symptoms in females. The disease is Charcot-Marie-Tooth disease X-linked dominant 1 (MONDO_0010549). Also known as: CMTX 1, CMTX1, Charcot Marie Tooth disease X-linked 1, Charcot-Marie-Tooth disease X-linked dominant type 1, Charcot-Marie-Tooth disease type X caused by mutation in GJB1, Charcot-Marie-Tooth disease, X-linked dominant, 1, Charcot-Marie-Tooth disease, X-linked dominant, type 1, Charcot-Marie-Tooth disease, X-linked, 1.