Monarch Disease Ontology entry MONDO_0010561 (Coffin-Lowry syndrome) is a rare X-linked syndromic intellectual disability characterized by global development delay, postnatal growth retardation leading to short stature, facial dysmorphism, short hands with tapering fingers and progressive skeletal abnormalities including kyphoscoliosis and pectus carinatum/excavatum. Intellectual disability ranges from mild to severe. Also known as: CLS, Coffin Lowry Syndrome, Coffin-Lowry syndrome, X-linked dominant.