X-linked mixed deafness with perilymphatic gusher, also known as X-linked deafness type 2, is a rare form of non-syndromic genetic deafnesss affecting males and characterized by pathognomonic inner ear anomalies and conductive and profound sensorineural hearing loss. The inner ear anomalies are described as dilatation of the internal auditory meatus and fistulous connection between the cochlear basal turn and internal auditory canal resulting in perilympatic gusher on attempted mobilization of a fixed stapes. Obligate female carriers may suffer from mild to moderate hearing loss. The disease is MONDO_0010576 (X-linked mixed hearing loss with perilymphatic gusher). Also known as: DFNX2, X-linked mixed conductive and neurosensory hearing loss, X-linked mixed conductive and sensorineural hearing loss, X-linked stapes gusher syndrome.