Monarch Disease Ontology term MONDO_0010651 (Menkes disease) is a usually severe multisystemic disorder of copper metabolism, characterized by progressive neurodegeneration and marked connective tissue anomalies as well as typical sparse abnormal steely hair. Also known as: MD, MNK, Menkes kinky hair syndrome, Menkes kinky-hair syndrome, Menkes syndrome, Mk, Trichopoliodystrophy, X-linked copper deficiency.