Partington syndrome (MONDO_0010654, a Monarch Disease Ontology id) can be described as follows. A rare neurological condition that is primarily characterized by mild to moderate intellectual disability and dystonia of the hands. Other signs and symptoms may include dysarthria, behavioral abnormalities, recurrent seizures and/or an unusual gait (style of walking). Partington syndrome usually occurs in males; when it occurs in females, the signs and symptoms are often less severe. It is caused by changes (mutations) in the ARX gene and is inherited in an X-linked recessive manner. Treatment is based on the signs and symptoms present in each person. Also known as: Partington syndrome, X-linked recessive, Partington-Mulley syndrome, X-linked Russell-Silver syndrome, X-linked intellectual disability-dystonia-dysarthria syndrome.