Wieacker-Wolff syndrome (MONDO_0010758) is a severe X-linked recessive neurodevelopmental disorder characterized by severe contractures (arthrogryposis) and intellectual disability. Also known as: MCS, MRXS4, Miles-CARPENTER X-linked mental retardation syndrome, Miles-Carpenter syndrome, WRWF, WRWFXLR, Wieacker Wolff syndrome, Wieacker syndrome.