Leber hereditary optic neuropathy (MONDO_0010788) can be described as follows. Leber's hereditary optic neuropathy (LHON) is a mitochondrial neurodegenerative disease affecting the optic nerve and often characterized by sudden vision loss in young adult carriers. Also known as: LHON, Leber Hereditary optic atrophy, Leber optic atrophy, Leber's hereditary optic neuropathy, Leber's optic atrophy.