MELAS (Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke) syndrome is a rare progressive multisystemic disorder characterized by encephalomyopathy, lactic acidosis, and stroke-like episodes. Other features include endocrinopathy, heart disease, diabetes, hearing loss, and neurological and psychiatric manifestations. The disease is MONDO_0010789 (MELAS syndrome). Also known as: mitochondrial encephalomyopathy, lactic acidosis and stroke, mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes, mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes, mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes.