CARASIL syndrome (MONDO_0010829) can be described as follows. CARASIL is a hereditary cerebral small vessel disease characterized by early-onset gait disturbances, premature scalp alopecia, ischemic stroke, acute mid to lower back pain and progressive cognitive disturbances leading to severe dementia. Also known as: CARASIL, Maeda syndrome, cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy.