Any amyotrophic lateral sclerosis in which the cause of the disease is a mutation in the SPG11 gene. The disease is Monarch Disease Ontology id MONDO_0011196 (amyotrophic lateral sclerosis type 5). Also known as: ALS5, SPG11 amyotrophic lateral sclerosis, amyotrophic lateral sclerosis 5, amyotrophic lateral sclerosis caused by mutation in SPG11.