spondyloepimetaphyseal dysplasia, Missouri type (MONDO_0011198) is a spondyloepimetaphyseal dysplasia characterized by moderate-to-severe metaphyseal changes, mild epiphyseal involvement, rhizomelic shortening of the lower limbs with bowing of the femora and/or tibiae, coxa vara, genu varum and pear-shaped vertebrae in childhood. Also known as: SEMD type 2, SEMD, Missouri type, spondyloepimetaphyseal dysplasia type 2.