Progressive familial intrahepatic cholestasis type 3 (PFIC3), a type of progressive familial intrahepatic cholestasis (PFIC), is a late-onset hereditary disorder in bile formation that is hepatocellular in origin. Onset may occur from infancy to young adulthood. The disease is progressive familial intrahepatic cholestasis type 3 (MONDO_0011214). Also known as: ABCB4 progressive familial intrahepatic cholestasis, MDR3 Deficiency, PFIC3, cholestasis, progressive familial intrahepatic 3, cholestasis, progressive familial intrahepatic, type 3, progressive familial intrahepatic cholestasis caused by mutation in ABCB4.