Any neurodegenerative disease with chorea in which the cause of the disease is a mutation in the PRNP gene. The disease is Huntington disease-like 1 (MONDO_0011299). Also known as: HDL1, HLN1, Huntington disease-like type 1, Huntington-like neurodegenerative disorder 1, PRNP neurodegenerative disease with chorea, autosomal dominant Huntington-like neurodegenerative disorder, early-onset prion disease with prominent psychiatric features, neurodegenerative disease with chorea caused by mutation in PRNP.