Any progressive external ophthalmoplegia with mitochondrial DNA deletions in which the cause of the disease is a mutation in the TWNK gene. The disease is progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 3 (MONDO_0012241). Also known as: TWNK progressive external ophthalmoplegia with mitochondrial DNA deletions, progressive external ophthalmoplegia with mitochondrial DNA deletions caused by mutation in TWNK, progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant type 3.