MONDO_0012335 (obesity due to pro-opiomelanocortin deficiency) can be described as follows. Pro-opiomelanocortin (POMC) deficiency is a form of monogenic obesity resulting in severe early-onset obesity, adrenal insufficiency, red hair and pale skin. Also known as: POMC Deficiency, POMC deficiency, obesity, adrenal insufficiency, and red hair due to POMC deficiency.