A rare condition that affects the nervous system. Signs and symptoms of the condition can develop any time from birth to adulthood and may include progressive dementia, seizures, lack of muscle coordination, and vision loss. CLN10-NCL is caused by changes (mutations) in the CTSD gene and is inherited in an autosomal recessive manner. Treatment options are limited to therapies that can help relieve some of the symptoms. The disease is MONDO_0012414 (neuronal ceroid lipofuscinosis 10). Also known as: CLN10, CLN10-NCL, CTSD neuronal ceroid lipofuscinosis, Cathepsin D deficiency, ceroid lipofuscinosis, neuronal, type 10, neuronal ceroid lipofuscinosis cathepsin D-deficient, neuronal ceroid lipofuscinosis caused by mutation in CTSD, neuronal ceroid lipofuscinosis due to cathepsin D deficiency.