hypercoagulability syndrome due to glycosylphosphatidylinositol deficiency (MONDO_0012465, a Monarch Disease Ontology id) is the combination of a propensity for venous thrombosis and seizures has been reported in two unrelated kindreds. Transmission is autosomal recessive. It results from a point mutation of PIGM, which reduces transcription of PIGM and blocks mannosylation of glycosylphosphatidylinositol (GPI), leading to partial but severe deficiency of GPI. Also known as: PIGM-CDG.