Any Leber congenital amaurosis in which the cause of the disease is a mutation in the RD3 gene. The disease is Leber congenital amaurosis 12 (Monarch Disease Ontology identifier MONDO_0012525). Also known as: LCA12, Leber congenital amaurosis caused by mutation in RD3, Leber congenital amaurosis type 12, RD3 Leber congenital amaurosis.