Any coronary artery disease in which the cause of the disease is a mutation in the LRP6 gene. The disease is coronary artery disease, autosomal dominant 2 (MONDO_0012586). Also known as: LRP6 coronary artery disease, coronary artery disease caused by mutation in LRP6, coronary artery disease, autosomal dominant type 2, coronary artery disease, autosomal dominant, 2.