Any Leber congenital amaurosis in which the cause of the disease is a mutation in the CEP290 gene. The disease is Monarch Disease Ontology term MONDO_0012723 (Leber congenital amaurosis 10). Also known as: CEP290 Leber congenital amaurosis, LCA10, Leber congenital amaurosis caused by mutation in CEP290, Leber congenital amaurosis type 10.