Any Aicardi-Goutieres syndrome in which the cause of the disease is a mutation in the SAMHD1 gene. The disease is Aicardi-Goutieres syndrome 5 (MONDO_0013059). Also known as: Aicardi-Goutieres syndrome caused by mutation in SAMHD1, Aicardi-Goutieres syndrome type 5, SAMHD1 Aicardi-Goutieres syndrome.