Congenital Tufting Enteropathy is a rare congenital enteropathy presenting with early-onset severe and intractable diarrhea that leads to irreversible intestinal failure. The disease is Monarch Disease Ontology entry MONDO_0013184 (congenital diarrhea 5 with tufting enteropathy). Also known as: DIAR5, EPCAM secretory diarrhea, EPCAM secretory diarrhoea, IED, congenital familial intractable diarrhea with epithelial or epithelium abnormalities, congenital familial intractable diarrhoea with epithelial or epithelium abnormalities, congenital tufting enteropathy, intestinal epithelial dysplasia.