Any hereditary nonpolyposis colon cancer in which the cause of the disease is a  heterozygous deletion of 3-prime exons of the EPCAM gene and intergenic regions directly upstream of the MSH2 gene, resulting in transcriptional read-through and epigenetic silencing of MSH2 in tissues expressing EPCAM. The disease is MONDO_0013196 (Lynch syndrome 8). Also known as: EPCAM hereditary nonpolyposis colon cancer, colorectal cancer, hereditary nonpolyposis, type 8, hereditary nonpolyposis colon cancer caused by mutation in EPCAM.