Alpha-1-antitrypsin deficiency is a hereditary disease that develops in adulthood and is characterized by chronic liver disorders (cirrhosis), respiratory disorders (emphysema), and rarely panniculitis. The disease is Monarch Disease Ontology entry MONDO_0013282 (alpha 1-antitrypsin deficiency). Also known as: A-1ATD, A1AD, AAT deficiency, Alpha-1 Antitrypsin Deficiency, deficiency in Alpa-1-proteinase inhibitor, emphysema due to AAT deficiency, emphysema-cirrhosis, due to AAT deficiency, hemorrhagic diathesis due to antithrombin pittsburgh.