Aromatase deficiency disrupts the synthesis of estradiol, resulting in hirsutism of mothers during gestation of an affected child; pseudohermaphroditism and virilization in women; and tall stature, osteoporosis and obesity in men. The disease is Monarch Disease Ontology id MONDO_0013301 (aromatase deficiency). Also known as: congenital estrogen deficiency, congenital oestrogen deficiency.