LEOPARD syndrome 3 (Monarch Disease Ontology term MONDO_0013380) is any Noonan syndrome with multiple lentigines in which the cause of the disease is a mutation in the BRAF gene. Also known as: BRAF Noonan syndrome with multiple lentigines, Leopard syndrome type 3, Noonan syndrome with multiple lentigines caused by mutation in BRAF, leopard syndrome 3.